Overview

A dosing and kinetics calculator for pharmacists. This calculator is intended to be used in conjunction with reasonable clinical judgement and current dosing protocols.

Features

• Creatinine clearance calculation (Cockroft-Gault for adults, Schwartz for peds)
• Vancomycin dosing
  • Initial protocol dosing
  • Initial pharmacokinetic dosing
  • Single level (trough) revision
  • AUC calculation
  • Two-level pharmacokinetics
• Second dose timing
• IVIG rate calculation and admin instruction generation
• Heparin calcualtor for transferred patients
• Aminoglycoside Extended Interval Dosing
• Custom QT Interval Correction
• PCA Calculator
• KCentra calculation and admin instruction generation
• Standard administration times tool
• Single and double alligation
• Warfarin average dose adjustment calculator

Documentation

• Equations and Calculations
• Code Documentation

Work In Progress

Release Notes

View full changelog here

[1.3.1] - 2025-01-07

Added

• Glucommander dosing calculator

Changed

• Change vancomycin calculations to reflect updated dosing guidelines
• Add support for black & white printing

1.2.3 - 2024-05-03

Changed

• PCA max accumulated dose per 1 hour for all therapies
• PCA pump limits updated to match new smart pumps

1.2.2 - 2024-01-02

Changed

• Remove AFib checkbox from QTc calculator

1.2.1 - 2023-10-11

Fixed

• Reset Button not resetting patient info

1.2.0 - 2023-10-06

Added

• Extended interval aminoglycoside calculator
• Vancomycin peak timing calculator
• Corrected QT interval calculator
• Single and double alligation calculator

1.1.0 - 2023-01-30

Added

• AMG Dosing Weight
• Body surface area calculatiom
• Reverse Heparin Calculator
• PCA Dosing Calculator
• Standard Administration Times tool
• KCentra Lot/Exp Calculator

Changed

• Add Privigen to IVIG options and make default

1.0.5 - 2022-11-24

Fixed

• Pediatric maintenance dose not being calculated

1.0.4 - 2022-10-02

Changed

• Added halflife to AUC calculation details

Fixed

• Disabled Bayesian recommendation if HD is selected
• Fixed error displaying details when levels are drawn in the same interval

1.0.3 - 2022-05-20

Changed

• Reword PK dosing disclaimer to consider using if large discrepancy from weight-based dosing
• Split webpack entry points and added copy-webpack-plugin for build optimization

1.0.2 - 2022-05-18

Changed

• Keep initial PK dosing disclaimer visible after button is clicked to show section
• Show link to Bayesian calculator instead of weight-based initial maintenance dose if BMI > 30
  • IDCG Request, May 2022

Fixed

• Age input in months and/or days

1.0.1 - 2022-04-06

Changed

• Increased allowed time between levels for AUC calculation (e.g. for q48h dosing)

1.0.0 - 2021-11-03

Added

• Documentation of PK equations and calculations
• Output of date and time inputs to calculation details

Changed

• Can now run independently if hosted on local server (will work if internet is down)

Fixed

• Trigger AUC calculation when inputs from modal are copied to calculator
• Clear data validation errors when form is reset

0.4.0 - 2021-10-21

New Features

• Output of inputs, outputs, and calculation steps
• Favicon

Bug Fixes

• Initial PK Dosing no longer changes if interval is modified after first calculation

0.3.0 - 2021-10-09

New Features

• Color change of Bayesian calculator alert when BMI > 30
• Hour calculator for AUC dosing
• Confirmation before showing initial PK recommendations
• Focus on age input when page loads
• Highlight BMI when above 30

Changes

• Reposition Bayesian calculator alert higher on page
• Modified monitoring recommendations to clarify when to draw trough

0.2.2 - 2021-08-19

New Features

• Alert with link to Bayesian calculator for initial PK dosing in kinetic outliers

Changes

• Updated wording of SSTI/UTI indication to match protocol update

0.2.1 - 2021-08-17

Changes

• New link to PDF of updated protocol

0.2.0 - 2021-07-18

Release for Go-Live of Vancomycin Dosing Protocol Update (Aug 2021)

New Features

• Pediatric vancomycin dosing recommendations
• Pediatric obesity check (using 95th percentile of bmi-for-age CDC data)
• IVIG rate calculator

Changes

• Initial PK dosing calculation modified to match Epic Kinetics Navigator
• Added dofetilide to list of drugs to always use ABW CrCl
• Reworded indication drop-down

0.1.1 - 2021-06-13

New Features

• Pediatric CrCl calculation using Schwartz equation
• Option to enter age in months and/or days instead of years

Changes

• Vancomycin initial dosing and monitoring per updated protocol

0.1.0 - 2021-06-02

Initial POC Release

Changes

• Minor bug fixes

0.0.3 - 2021-06-02

New Features

• Second dose timing tab
• Card footer for CrCl explaining which value to use
• Dose adjustment recommendation for HD patients
• Option to adjust the recommended dose/frequency in PK calculations (initial and adjustment)
• Reset button to undo adjustments made to default/recommended dose/frequency
• Table of dose options and resulting troughs for initial PK calculation

Bug Fixes

• Validation of time inputs

0.0.2 - 2021-05-19

Changes

• Switched order of height and weight inputs to match Epic
• Removed SCr IDMS conversion (per TEAM Core Group)

0.0.1 - 2021-04-23

Initial pre-release for distribution among liaisons/vanco calc workgroup