Global

Methods

changedAmgMethod()

Check CF box status and show/hide DOM elements based on dosing method

Source:

displayChange(el, d, f) → {HTMLElement}

From a proposed dose and frequency, calculate and display the percent change from the patient's current total daily dose.

Parameters:
Name Type Default Description
el String | HTMLElement

jQuery selector for element that will display result
d Number | String 0

the dose in mg
f Number | String 0

the frequency (every __ hours)
Source:
Requires:

module:formValidation(config) → {String}

Set up event listeners for form validation

Parameters:
Name Type Description
config Array.<FormValidationConfig>

configuration for setup
Source:

resetDates()

Resets date input fields to today's date.

Source:

vancoColorScale(x) → {String}

Provides a color to highlight the percent change of total daily vancomycin dose. Color stops are fixed at : red at 35%, yellow at 30%, and green at 20% Values in between color stops are scaled using R, G, and B values

Parameters:
Name Type Description
x Number

percent change (from -100 to 100)
Source:

Type Definitions

AlligationCheck :Object

Input validity check

Properties:
Name Type Attributes Default Description
errMessage String

Error message to display if check fails
check Boolean

Expression to evaluate that returns true if valid
ignoreSingle Boolean <optional>
 false

Ignore this check for single alligation
ignoreDouble Boolean <optional>
 false

Ignore this check for double alligation
markInvalid String <optional>

jQuery selector of element to mark as invalid if check fails
Source:

AlligationResult :Object

Alligation Result

Properties:
Name Type Description
err String

Error text if calculation is not possible
components Array.<AlligationResultRow>

Components that make the final solution
final AlligationResultRow

Details of final solution
Source:

AlligationResultRow :Object

Alligation Result Row

Properties:
Name Type Description
amount String

Amount and units of the solution
description String

Description of the solution
Source:

AmgExtendedResult :Object

Aminoglycoside Extended Interval Calculation Results

Properties:
Name Type Attributes Default Description
ke Number

Elinimation rate constant in (1/hr), or 0 if insufficient inputs
truePeak Number

True peak level in mcg/mL, or 0 if insufficient inputs
troughDT Date

Date and time of goal trough/target MIC, or 0 if insufficient inputs
redoseDT Date

Date and time of redose point, or 0 if insufficient inputs
redoseLevel Number

Estimated level at redose point, or undefined if insufficient inputs
newDoseToRedoseTime Date

Time from start of new dose to redose point, or 0 if insufficient inputs
vd Number

Volume of distribution, or 0 if insufficient inputs
recDose Number

Recommended new dose in mg, or 0 if insufficient inputs
recFreq Number

Recommended new frequency to the nearest 12 hours, or 0 if insufficient inputs
levelAtCustom Number

Estimated level at custom date and time, or undefined if insufficient inputs
warn Boolean

Show warning that distribution may not be complete
valid Boolean <optional>
 true

Set to false if inputs already known to be invalid
Source:

AmgParams :Object

Aminoglycoside Calculation Parameters

Properties:
Name Type Description
drug String

The selected drug, as a single uppercase letter: [G]entamicin, [T]obramycin, or [A]mikacin
goalPeak Number

Goal peak level in mcg/mL
dose Number

Current dose in mg
doseTime Date

Date and time of dose
postAbxEffect Number

Post antibiotic effect, in hours
level1 Number

First level in mcg/mL
level1Time Date

Date and time of first level
level2 Number

Second level in mcg/mL
level12ime Date

Date and time of second level
customTime Date

Date and time for custom estimation
Source:

AucCalcParams :Object

Vancomycin AUC Calculation Parameters

Properties:
Name Type Description
dose Number

Current dose in mg
interval Number

Current interval in hours
trough Number

Current measured trough
peak Number

Current measured peak
troughTime Number

Time from dose to trough in hours
peakTime Number

Time from dose to peak in hours
Source:

AucCurrent :Object

Calculated AUC results

Properties:
Name Type Description
vd Number

Volume of distribution
ke Number

Elimination rate constant
halflife Number

Halflife
auc24 Number

AUC 24
aucInf Number

AUC_infusion
aucElim Number

AUC_elimination
truePeak Number

True peak level
trueTrough Number

True trough level
tInf Number

Infusion time
therapeutic String

[subtherapeutic|supratherapeutic|therapeutic]
oldDose Number

Current dose in mg
oldInterval Number

Current interval in hours
goalTroughLow Number

Bottom of personalized goal trough range
goalTroughHigh Number

Top of personalized goal trough range
Source:

AucNew :Object

Calculated AUC results for various possible doses with the selected interval, for output to a table

Properties:
Name Type Description
dose Array.<Number>

New dose in mg
auc Array.<Number>

Predicted AUC from new dose
infTime Array.<Number>

Infusion time in hours
trough Array.<Number>

Calculated trough level
peak Array.<Number>

Calculated peak level
therapeutic Array.<Boolean>

If resulting AUC is therapeutic
Source:

DosingWeightParams :Object

Parameters for calculating AMG dosing weight

Properties:
Name Type Description
alt Boolean

Use alternate dosing weight
age Number

Patient age in years
wt Number

Patient weight in kg
ibw Number

Ideal body weight in kg
adjBW Number

Adjusted body weight in kg
overUnder Number

Percent over or under ideal body weight
Source:

DosingWtResults :Object

Results from AMG dosing weight calculations

Properties:
Name Type Description
dosingWeight Number

Dosing weight in kg
dosingWeightType String

Weight type
dosingWeightReason String

Reason for using specified weight
dosingWeightString String

Full HTML string for display
Source:

GlucommanderParams :Object

Properties:
Name Type Description
ident String

identifier to use for DOM updates
tdd Number

total daily dose
percentBasal Number

percent of daily dose that's basal
percentReduction Number

percent reduction from PTA TDD
basal Number

total daily basal dose
bolus Number

total daily bolus dose
breakfast Number

breakfast bolus dose
lunch Number

lunch bolus dose
dinner Number

dinner bolus dose
dir String

direction of calculation (for custom dose)
oppDir String

opposite direction of calculation (for custom dose)
Source:

LoadConfig :Object

Loading dose configuration

Properties:
Name Type Description
low Number

low end of loading dose range in mg/kg
high Number

high end of loading dose range in mg/kg
max Number

max loading dose in mg
Source:

PcaLimit :Object

Hard and soft limits. null if not applicable, 0 if not set.

Properties:
Name Type Description
soft Number

Soft limit
hard Number

Hard limit
Source:

PcaLimitMinMax :Object

All values for one type of PCA limit

Properties:
Name Type Description
min PcaLimit

Minimum limits
max PcaLimit

Maximum limits
Source:

PcaLimitSet :Object

Alaris Guardrails PCA Limits for one drug and therapy

Properties:
Name Type Description
pca PcaLimitMinMax

Limits for patient-delivered PCA dose
continuous PcaLimitMinMax

Limits for continuous infusion rate per hour
bolus PcaLimitMinMax

Limits for clinician-delivered bolus
load PcaLimitMinMax

Limits for clinician-delivered loading dose
lockout PcaLimitMinMax

Limits for lockout interval in minutes
accumulated PcaLimitMinMax

Limits for max accumulated dose in one hour
Source:

PcaOptions :Object

PCA Options for one drug and therapy

Properties:
Name Type Description
drugName String

Drug name
dosingUnit String

Unit (mg or mcg)
concentration Number

Concentration in per mL
volume Number

Total volume of PCA in mL
maxIncludesBolus Boolean

Whether clinician-delivered bolus is included in accumulated dose calculation
limits PcaLimitSet

Alaris Guardrails PCA settings
Source:

PcaParams :Object

PCA Order Parameters

Properties:
Name Type Description
pca Number

patient-delivered PCA dose
rate Number

continuous infusion rate per hour
lockout Number

lockout interval in minutes
max Number

max accumulated dose in one hour
Source:

QTCalcParams :Object

QT Calculation Parameters

Properties:
Name Type Description
hr Number

heart rate
qrs Number

QRS interval
qt Number

QT interval or shortest QT interval for Afib
Source:

QtcResult :Object

QTc calculation result

Properties:
Name Type Description
method String

Method used for calculation
value Number | String

Corrected QT interval, or empty string if invalid/insufficient inputs
Source:

VancoClCrassParams :Object

Vancomycin Clearance Calculation Parameters for Crass method

Properties:
Name Type Description
age Number

Age in years
scr Number

Serum creatinine in mg/dL
sex String | Number

Sex (expects "M", "F", or 0)
wt Number

Weight in kg
Source:

VancoConfig :Object

Vancomycin Configuration

Properties:
Name Type Description
doses Array.<Number>

Standard maintenance doses to use for dose tables
load VancoLoadConfigParams

Loading dose parameters
check VancoInputLimits

Acceptable input values for input validation
maxHDDose Number

Maximum initial maintenance dose for HD patients
maxPDDose Number

Maximum initial maintenance dose for PD patients
maxDaily Number

Maximum initial total daily dose
aucLowNormal Number

Low normal AUC value
aucHighNormal Number

High normal AUC value
Source:

VancoHdRevParams :Object

Vanco HD Revision Result

Properties:
Name Type Description
wt Number

Patient's weight in kg
trough Number

Measured trough level
timing Number

When was level drawn? 0 = pre-HD, 1 = post-HD
goal Number

Goal trough: 0 = 10-20, 1 = 10-15, 2 = 10-20
hd Number

HD type (as selectedIndex)
Source:

VancoInitialPkParams :Object

Vancomycin Initial PK Dosing Parameters

Properties:
Name Type Attributes Default Description
method Number
crcl Number

Creatinine clearance in mL/min
age Number

Age in years
scr Number

Serum creatinine in mg/dL
sex String | Number

Sex (expects "M", "F", or 0)
wt Number

Weight in kg
bmi Number

Body mass index in kg/m^2
infTime Number <optional>
 1

Infusion time in hours
goalMin Number

Bottom of goal range
goalMax Number

Top of goal range
selDose Number

Selected dose in mg
selFreq Number

Selected frequency in hours
Source:

VancoInitialPkResult :Object

Vanco Initial PK Dosing Result

Properties:
Name Type Description
vd Number

Volume of distribution in L
pkHalflife Number

Halflife in hours
ke Number

Elimination rate constant
arrDose Array.<Number>

Possible doses
arrViable Array.<Boolean>

Whether dose is viable
arrLevel Array.<Number>

Expected level for dose
pkFreq Number

Selected frequency or recommended frequency if none selected
pkLevel Number

Expected level from selected frequency
pkRecDose Number

Recommended dose in mg
pkRecFreq Number

Recommended frequency in hours
pkRecLevel Number

Expected level from recommended dose and frequency
Source:

VancoInputLimits :Object

Vancomycin Input Validation Parameters

Properties:
Name Type Description
doseMin Number

minimum acceptable dose input
doseMax Number

maximum acceptable dose input
freqMin Number

minimum acceptable frequency input
freqMax Number

maximum acceptable frequency input
levelMin Number

minimum acceptable level input
levelMax Number

maximum acceptable level input
timeMin Number

minimum acceptable dose-to-level time input for AUC calculation
timeMax Number

maximum acceptable dose-to-level time input for AUC calculation
infTimeMin Number

minimum acceptable infusion time
infTimeMax Number

maximum acceptable infusion time
Source:

VancoLinearParams :Object

Single level linear adjustment calculation parameters

Properties:
Name Type Description
curDose Number

Current dose in mg
curFreq Number

Current frequency in hours
curTrough Number

Current trough in mg/dL
testDose Number

Selected dose in mg
testFreq Number

Selected frequency in hours
goalTrough Number

Middle of goal trough range in mg/dL
Source:

VancoLinearResults :Object

Single level linear adjustment calculation results

Properties:
Name Type Description
linearDose Number

Calculated dose for linear adjustment in mg
linearFreq Number

Calculated frequency for linear adjustment in hours
linearTrough Number

Estimated trough from calculated dose/frequency
testLinearDose Number

Test dose from input parameters if all inputs are valid
testLinearFreq Number

Test frequency from input parameters if all inputs are valid
testLinearTrough Number

Est trough from test dose and test frequency
Source:

VancoLoadConfigParams :Object

Loading Dose Paramaters

Properties:
Name Type Description
def LoadConfig

LD parameters for most patients
sepsis LoadConfig

LD parameters for severe sepsis
hd LoadConfig

LD parameters for hemodialysis
pd LoadConfig

LD parameters for peritoneal dialysis
crrt LoadConfig

LD parameters for CRRT (CVVH, CVVHD, CVVHDF)
sled LoadConfig

LD parameters for SLED
Source:

VancoLoadParams :Object

Vancomycin Loading Dose Calculation Parameters

Properties:
Name Type Description
ht Number

Height in cm
wt Number

Weight in kg
age Number

Age in years
sex String | Number

Sex (expects "M", "F", or 0)
bmi Number

Body mass index in kg/m^2
hd Number

Selected index of HD combo box (0=No, 1=HD, 2=PD, 3=CRRT, 4=SLED)
vancoIndication Number

Selected index of indication combo box (0=default, 1=SSTI/UTI, 2=severe sepsis, 3=CNS, 4=CNS and severe sepsis)
Source:

VancoMaintRangeParams :Object

Vancomycin initial maintenance dose range calculation parameters

Properties:
Name Type Description
age Number

patient age in years
indication Number

selectedIndex of indication list
crcl Number

CrCl to use for dosing
hd Number

selectedIndex of HD status
aki Boolean

patient is in AKI
Source:

VancoMaintRangeResult :Object

Vancomycin initial maintenance dose range calculation result

Properties:
Name Type Description
low Number

low end of dose range
high Number

high end of dose range
lowDailyPeds Number

low end of dose range (per day - for peds)
highDailyPeds Number

high end of dose range (per day - for peds)
consider Number

consider dosing closer to this end of range
freqs Array.<Number>

two choices of frequency
freq Number

frequency (this or the below property)
freqText String

string frequency if number frequency is not applicable
maxDaily Number

max daily dose (one or the other of this or below)
maxDose Number

max single dose
maxDoseExceededText String

text to append if dose exceeds max single dose
textBeforeDose String

text to prepend
Source:

VancoMaintRecParams :Object

Vancomycin Maintenance Dose Recommendation Parameters

Properties:
Name Type Description
age Number

Age in years
wt Number

Weight in kg
ibw Number

Ideal body weight in kg
scr Number

Serum creatinine in mg/dL
crcl Number

Creatinine clearance in mL/min
hd Number

Selected index of HD combo box (0=No, 1=HD, 2=PD, 3=CRRT, 4=SLED)
indication Number

Selected index of indication combo box (0=default, 1=SSTI/UTI, 2=severe sepsis, 3=CNS, 4=CNS and severe sepsis)
aki Boolean

Patient is in AKI
Source:

VancoPeakTroughParams :Object

Vanco peak and trough calculation parameters

Properties:
Name Type Description
dose Number

Dose in mg
ke Number

Elimination rate constant
inf Number

Infusion time in hours
vd Number

Volume of distribution in L
interval Number

Interval in hours
Source:

VancoPeakTroughResult :Object

Vanco peak and trough calculation result

Properties:
Name Type Description
p Number

Calculated peak level
tr Number

Calculated trough level
Source:

VancoProtMonRecParams :Object

Vancomycin Per-Protocol Monitoring Recommendation Parameters

Properties:
Name Type Description
freq Number

Frequency in hours
hd Number

Dialysis status as selectedIndex
crcl Number

Creatinine clearance in mL/min
scr Number

Serum creatinine in mg/dL
bmi Number

Body mass index in kg/m^2
indication Number

Indication as selectedIndex
age Number

Age in years
aki Boolean

Patient is in AKI
outlier Boolean

Patient is a PK outlier
Source:

VancoProtMonRecResult :Object

Vancomycin Per-Protocol Monitoring Recommendation Result

Properties:
Name Type Description
monitoring String

Monitoring recommendation as HTML string
targetLevelText String

Target level as HTML string
method String

Dosing method as HTML string (e.g. weight-based or InsightRx)
targetMin Number

Bottom of target range
targetMax Number

Top of target range
goalTroughIndex Number

Goal trough as selectedIndex
Source:

VancoSingleAdjParams :Object

Vancomycin Single Level Adjustment Parameters

Properties:
Name Type Description
bmi Number

Body mass index in kg/m^2
wt Number

Weight in kg
curDose Number

Current dose in mg
curFreq Number

Current frequency in hours
curTrough Number

Measured trough in mg/dL
troughTime Number

Time before next dose that trough was drawn
goalTrough Number

Middle of goal trough range
goalMin Number

Minimum of goal trough range
goalMax Number

Maximum of goal trough range
goalPeak Number

Goal peak level
selFreq Number

Selected new frequency
selDose Number

Selected new dose
Source:

VancoSingleAdjResult :Object

Vancomycin Single Level Adjustment Result

Properties:
Name Type Description
newDose Array.<Number>

Possible new doses
newTrough Array.<Number>

Troughs from newDose and newFreq
newViable Array.<Boolean>

Whether newTrough is within target range
recFreq Number

Recommended new frequency
selFreq Number

Selected new frequency from input parameters if all inputs are valid
newFreq Number

selFreq if defined, otherwise recFreq
recDose Number

Recommended new dose
selDose Number

Selected new dose from input parameters if all inputs are valid
newDose Number

selDose if defined, otherwise recDose
recTrough Number

Calculated trough from recDose and recFreq
selTrough Number

Calculated trough from selDose and selFreq
newTrough Number

Calculated trough from newDose and newFreq
Source:

VancoTwolevelParams :Object

Vancomycin Two-Level PK Calculation Parameters

Properties:
Name Type Description
wt Number

Weight in kg
bmi Number

Body mass index in kg/m^2
ke Number

Elimination rate constant
selectedInterval Number

Selected interval in hours
Source:

VancoTwolevelResult :Object

Vancomycin Two-Level PK Calculation Result

Properties:
Name Type Description
vd Number

Volume of distribution
halflife Number

Halflife in hours (from obj.ke)
newDose Array.<Number>

Possible new doses
infTime Array.<Number>

Infusion time for new doses
newPeak Array.<Number>

Peaks from newDose and newFreq
newTrough Array.<Number>

Troughs from newDose and newFreq
newViable Array.<Boolean>

Whether newTrough is within target range
pkFreq Number

Recommended frequency (or selected frequency if chosen)
pkDose Number

Recommended dose given pkFreq
pkTrough Number

Estimated torugh from pkDose and pkFreq
Source:

VancoVdParams :Object

Vancomycin Volume of Distribution Calculation Parameters

Properties:
Name Type Description
bmi Number

Body mass index in kg/m^2
wt Number

Weight in kg
Source: